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Grieving Process

Incidence Rate

Causes & Treatments
  • Anatomic
  • Hormonal
  • Chromosomal
  • Immunologic
  • Miscellaneous

Clinical Evaluation

Endocrine Mechanism

There are two primary modes of communication between cells within the human body: systems of hormones (the endocrine system) and systems of neurons (the nervous system). These systems use chemical messengers to mediate their actions.

Hormones are “messengers” that may act on the cell that released it (autocrine mechanism), an adjacent cell (paracrine mechanism), or a distant cell following release of the hormone into the bloodstream (endocrine mechanism). After endocrine glands secrete hormones into the circulation a distant cell (equipped with a highly specific receptor for only that particular hormone) will recognize and bind the circulating hormone to trigger a biological response.

The reproductive hormone system involves pituitary hormones that act on the ovaries, and the ovarian hormones that are produced then act on the uterus. The hormone problem that has been most associated with recurrent pregnancy loss is (ovarian) progesterone insufficiency.



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The NJ Center for Fertility and Reproductive Medicine